Actionable Strategies for Concurrent Use Measures:
Poly-ACH and COB
Posted by PHN Communications | Nov 20, 2025 | Reminders
Once patients are noncompliant for the following measures, they cannot be made compliant for the rest of the year:
Concurrent Use of Opioids and Benzodiazepines (COB)
Polypharmacy: Use of Multiple Anticholinergic Medications in Older Adults (Poly-ACH)
Consider these best practices to reduce risk and improve compliance:
Prescribe covered alternatives if clinically appropriate.
Limit refills and auto-refills to allow for interventions to assess the appropriateness of continued therapy.
Limit dosages and durations to the minimum possible while achieving the desired clinical effect.
For COB: Check the Louisiana Prescription Monitoring Program to verify that patients are not being prescribed controlled substances by other providers.
For Poly-ACH:
Identify patients prescribed two or more ACH medications.
Regularly re-evaluate the efficacy and risks of ACH medications, especially for treatment periods longer than three months because of the potential for irreversible cognitive effects.
When prescribing to older adults, prioritize medications with fewer ACH effects and high effectiveness at the target site.